头针对脑梗死后脑灰质损伤干预作用的影像学研究

郎奕1,2 崔方圆2 李匡时2 谭中建2 邹忆怀2

(1.北京大学人民医院中医科, 北京 100044)
(2.北京中医药大学东直门医院脑病科, 北京 100700)

【摘要】目的 采用基于体素形态学方法,研究脑梗死患者脑灰质结构损伤变化特点及头针疗法的干预作用。方法 选取健康志愿者16名和脑梗死患者16例,将脑梗死患者随机分为头针组、对照组各8例,健康志愿者为正常组。所有患者行T1结构像扫描。采用VBM8软件包进行图像后处理,分别比较头针组、对照组治疗前后与正常组脑灰质结构差异。结果 脑梗死后患者较正常组在扣带回、楔前叶、楔叶、中央前回、脑岛等14个脑区存在脑灰质结构损伤,主要分布于患侧脑区。治疗两周后头针组较正常组在双侧舌回、后扣带回,左侧楔叶,右侧楔前叶等8个脑区仍存在灰质结构损伤,其中舌回和后扣带回2个脑区属新发脑灰质损伤。治疗两周后对照组较正常组在双侧前扣带、尾状核、楔叶、脑岛、额下回、额内侧回、楔前叶、旁中央小叶、颞上回、颞中回、舌回,右侧中央后回、后扣带回、中央前回、额中回等共计23个脑区存在脑灰质结构损伤,其中舌回、后扣带回、中央后回等9个脑区属新发脑灰质损伤。结论 脑梗死后脑灰质结构存在广泛损伤,随病程延长灰质体积可逐渐减少,联合应用头穴针刺疗法能有效抑制脑梗后脑灰质损伤的进程。

【关键词】 头针; 脑梗死; 体素形态学; 脑灰质;

【DOI】

【基金资助】 国家自然科学基金面上项目(No.81473667) 北京高校青年英才(No.YETP0822)

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This Article

ISSN:1003-5370

CN: 11-2787/R

Vol 36, No. 03, Pages 294-299

March 2016

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摘要

  • 资料与方法
  • 结果
  • 讨论
  • 参考文献