Chemical Constituents from Lagotis brachystachy
(2.School of Humanities, Jiangxi University of Traditional Chinese Medicine, Nanchang, China 330004)
【Abstract】Objective: To study the chemical constituents of Lagotis brachystachy. Methods: L. brachystachy was extracted with 75% ethanol and isolated and purified by silica gel, Sephadex LH-20, preparative liquid chromatography, ODS column chromatography, and recrystallization. The chemical structures were identified by spectrum analysis. Results: Eleven compounds were isolated and identified as scutellariosid II (1), globularimin (2), baldaccioside (3), 10-O-trans-isoferoylcatalpol (4), 8-epi-loganic acid (5), luteolin-7-O-β-D-glucopyranoside (6), tricin-7-O-β-D-glucopyranoside (7), luteolin (8), hemiphroside B (9), plantaginin D (10), benzyl alcohol-O-(2′-O-β-D-pyranoxylol)-β-D-glucopyranoside (11). Conclusion: Compounds 3, 4, 9, 10, and 11 are isolated from the Logotis genus for the first time. Compounds 1, 2, 5, and 7 are isolated from L. brachystachy for the first time.
【Keywords】 Lagotis brachystachy Maxim.; Chemical constituents; Structural identification;
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