Chemical Constitutes from Root of Artocarpus styracifolius
【Abstract】Objective: To study the chemical constituents from root of Artocarpus styracifolius. Methods: The constituents were isolated from the root of Artocarpus styracifolius by column chromatography over silica gel, RP-18 silica gel, MCI GEL CHP-20P, macroporous resin HP-20, Sephadex LH-20, Toyopearl HW-40C and by preparative HPLC. Their structures were elucidated by analysis of physical and chemical properties and spectral data. Results: Nine compounds were isolated and their structures were identified as p-hydroxy benzoic acid (1), syringic acid (2), 2, 4-dihydroxy benzaldehyde (3), (+)-lyoniresinol (4), 5, 5'-dimethoxysecoisolariciresinol (5), (+)-syringaresinol (6), scopoletin (7), xylarolide (8) and trans-oxyresveratrol (9). Conclusion: Compounds 2, 5, 6 and 8 are isolated from Moraceae for the first time. Compounds 1, 4 and 7 are firstly characterized in the genus Artocarpus, compounds 3 and 9 are characterized in Artocarpus styracifolius for the first time.
【Keywords】 Moraceae; Artocarpus; Lignans; Stilbene; Phenolic acids;
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