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Chemical constituents in chloroform fraction of Houttuynia cordata

YANG Xiao-lu1 YANG Yu-ping1 GE Yue-wei1 MENG Jiang

(1.School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica, National Administration of Traditional Chinese Medicine of People's Republic of China, Engineering Technology Research Center for Chinese Materia Medica Quality of Universities in Guangdong Province, Guangzhou, Guangdong Province, China 510006)

【Abstract】Nine compounds were isolated from chloroform fraction of Houttuynia cordata, and the isolates were identified as (S)-5, 6, 6a, 7-tetrahydro-2, 10-dimethoxy-4H-dibenzo[DE, G]quinoline-1, 9-diol (1), (+)-isoboldineβ-N-oxide (2), liriotulipiferine (3), telitoxinone (4), isoboldine (5), (-)-clovane-2β, 9α-diol (6), benzoic acid (7), acantrifoside E (8), and dibutyl phthalate (9). Among them, compound 1 was new, and compounds 2–9were reported from this species for the first time.

【Keywords】 Houttuynia cordata; chloroform fraction; chemical constituents; aporphine alkaloid;


【Funds】 Foundation for Distinguished Young Talents in Higher Education of Guangdong (YCJ [2008] No. 342)

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This Article


CN: 11-2272/R

Vol 44, No. 02, Pages 314-318

January 2019


Article Outline


  • 1 Materials
  • 2 Extraction and isolation
  • 3 Structural identification
  • 4 Discussion
  • References