Optimization of integration of field processing and processing crude drugs of Polygoni Multiflori Radix
(2.Suzhou Hospital of Chinese Medicine, Suzhou, Jiangsu Province, China 215003)
(3.Guizhou Changhao Chinese Medicine Development Co., Ltd., Kaili, Guizhou Province, China 556000)
【Abstract】Objective To optimize a technology of integration on field processing and processing crude drugs of Polygoni Multiflori Radix (PMR) and to provide the scientific evidence for the integration of PMR. Methods Orthogonal test was used to optimize the integration technology on primary processing and reprocessing with two major characteristic components (stilbene glucoside and combined anthraquinone). To compare the differences between the integration technology and traditional technology on pharmacological activity by models of constipation and swelling of ear in mice with Various index (small intestinal propulsion rate, first defecation time, fecal water content, swelling degree of ear, and inflammatory factors). Results The results showed that the integration technology of 50 °C, 16 h was better, and there was significant difference in chemical composition and laxative effect between the integration technology and traditional technology. The anti-inflammatory effect of the integrated process was better than that of the traditional technology. Conclusion The technology of integration of field processing and processing crude drugs is feasible and the operation is good.
【Keywords】 Polygoni Multiflori Radix; integration technology of field processing and processing crude drugs; traditional technology; orthogonal test; comprehensive scoring method; laxative effect; anti-inflammation; stilbene glucoside; combined anthraquinone;
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