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Brief

China Journal of Chinese Materia Medica, the 1st in the field of TCM, is supervised by China Association for Science and Technology and sponsored by Institute of Chinese Pharmaceutical Association. The journal is China's earliest comprehensive core journal of traditional Chinese medicine, and always maintains the circulation top in the professional areas. The journal publishes the latest research and progress of traditional Chinese medicine and takes a leading position in numbers of articles published, downloads and citations among all journals in this discipline. Its scope covers new achievements, technologies, methods, experiences and concepts resulting from the research on Chinese materia medica pursuant to Chinese medical and pharmaceutical theories, traditional experiences, and modern science and technology, including medicinal resources and identification, cultivation, processing, preparation, chemistry, pharmacology, theory of Chinese pharmacy and clinical practice, bencaological study. The journal is included in CA, JST and CSCD.
Editorial Board

Honorary Editor-in-Chief
Xiao Peigen
Editor-in-Chief
Wang Yongyan

Associate Editors
Zhang Boli, Hu Zhibi, Yao Xinsheng, Li Lianda, Li Dapeng, Yang Baofeng, Zhou Chaofan, Huang Luqi, Chen Shilin, Li He.

Executive Editorial Board
Cai Shaoqing, Chen Shilin

A new sesquiterpene from Acorus calamus (Ⅱ)

LI Juan;LI Zhao-xing;ZHAO Xiao-fang;XU Bo;LI Lin;ZHANG Lan;LI Shun-xiang

China Journal of Chinese Materia Medica,2017,Vol 42,No. 04

Cloning and expression analysis on full length CDS of zeaxanthin epoxidase gene in Pseudostellaria heterophylla

ZHENG Wei;ZHOU Tao;LI Jun;LONG Deng-kai;JIANG Wei-ke;DING Ling

China Journal of Chinese Materia Medica,2017,Vol 42,No. 04

Effects of Frankincense and Myrrh essential oil on transdermal absorption in vitro of Chuanxiong and penetration mechanism of skin blood flow

ZHU Xiao-fang;LUO Jing;GUAN Yong-mei;YU Ya-ting;JIN Chen;ZHU Wei-feng;LIU Hong-ning

China Journal of Chinese Materia Medica,2017,Vol 42,No. 04

The aim of this paper was to explore the effects of Frankincense and Myrrh essential oil on transdermal absorption in vitro of Chuanxiong, and to investigate the possible penetration mechanism of their essential oil from the perspective of skin blood perfusion changes. Transdermal tests were performed in vitro with excised mice skin by improved Franz diffusion cells. The cumulative penetration amounts of ferulic acid in Chuanxiong were determined by HPLC to investigate the effects of Frankincense and Myrrh essential oil on transdermal permeation properties of Chuanxiong. Simultaneously, the skin blood flows were determined by laser flow doppler. The results showed that the cumulative penetration amount of ferulic acid in Chuanxiong was (8.13 ± 0.76) μg·cm−2 in 24 h, and was (48.91 ± 4.87), (57.80 ± 2.86), (63.34 ± 4.56), (54.17 ± 4.40), (62.52 ± 7.79) μg·cm−2 respectively in azone group, Frankincense essential oil group, Myrrh essential oil, frankincense and myrrh singly extracted essential oil mixture group, and frankincense and myrrh mixed extraction essential oil group. The enhancement ratios of each essential oil groups were 7.68, 8.26, 7.26, 8.28, which were slightly greater than 6.55 in azone group. In addition, as compared with the conditions before treatment, there were significant differences and obvious increasing trend in blood flow of rats in Frankincense essential oil group, Myrrh essential oil group, frankincense and myrrh singly extracted essential oil mixture group, and frankincense and myrrh mixed extraction essential oil group when were dosed at 10, 20, 30, 10 min respectively, indicating that the skin blood flows were increased under the effects of Frankincense and Myrrh essential oil to a certain extent. Thus, Frankincense and Myrrh essential oil had certain effect on promoting permeability of Chuanxiong both before and after drug combination, and may promote the elimination of drugs from epidermis to dermal capillaries through increase of skin blood flow, thus enhancing the transdermal permeation amounts of drugs.

Analysis of transcriptomes and exploring flavonoid biosynthetic pathway genes in Lithocarpus polystachyus

SONG Ju;HUANG Jian;LI Zhi-dong;LONG Yue-hong;XING Zhao-bin

China Journal of Chinese Materia Medica,2017,Vol 42,No. 04

Multi-compound pharmacokinetic research on Chinese herbal medicines: approach and methodology

LI Chuan

China Journal of Chinese Materia Medica,2017,Vol 42,No. 04