Sponsor(s): Tianjin Institute of Pharmaceutical Research；Chinese Pharmaceutical Association
24 issues per year
Current Issue: Issue 08, 2015
Chinese Traditional and Herbal Drugs is supervised by Chinese Pharmaceutical Association and sponsored by Tianjin Institute of Pharmaceutical Research and Chinese Pharmaceutical Association. Launched in 1970, the journal is an academic journal with a broad scope in publishing research papers, brief reports, reviews, dissertations, and special treatises on the recent achievements of basic study, production, quality control, and clinic application on traditional Chinese medicine and Chinese materia medica. The journal is included in CA, JST and CSCD.
Chinese Traditional and Herbal Drugs,2015,Vol 46,No. 08
Objective Through studying the rationalization of alcohol precipitation process of Liuwei Dihuang Prescription to obtain the stable alcohol precipitation process which could be used to promote industrialization. Methods Such evaluation indexes as mass fraction, relative molecular weight distribution and extracts of loganin, peoniflorin, morroniside, manninotriose, and polysaccharides were taken as the evaluation indexes to investigate the addition method of ethanol and centrifugation, and the necessity of ethanol rinsing, so as to screen out the optimal alcohol precipitation process. Results It was reasonable to calculate the alcohol volume with volumetric method in the alcohol precipitation process. The polysaccharides and supernatant could be efficiently separated by ethanol rinsing. The polysaccharide extract and the contents of glycosides and manninotriose were up to the standard after the process was improved. Conclusion The optimized alcohol precipitation process is easy to operate with good controllability and repeatability. It is worthy of popularization and application for industrialization.