Sponsor(s):Chinese Optical Society；Shanghai Institute of Optics and Fine Mechanics，Chinese Academy of Sciences
12 issues per year
Current Issue: Issue 04, 2020
Acta Optica Sinica(ISSN：0253-2239), founded in 1981, is the optical academic publication issued at home and abroad, which covers the latest research in optical science. The main scopes of this journal include atmospheric and ocean optics, detectors, fiber optics and optical communications, Fourier optics and optical signal processing, holography, imaging systems, measurement and metrology, lasers and laser optics, machine vision, materials, nonlinear optics, optical design and fabrication, optical devices, physical optics, quantum optics, remote sensing and sensors, spectroscopy, X-ray optics, etc. This journal offers service for optical science and technology researcher to carry out academic exchange and discussion. Acta Optica Sinica has been selected into Science Abstracts(SA), Chemical Abstract (CA), Abstract Journal(AJ), Information Service in Physics, Electro-Technology, Computer and Control (INSPEC), Engineering Index (EI), etc, which is one of 100 outstanding academic journals of China.
Gan Fuxi Wang Zhijiang Xu Zhizhan Wang Runwen
Shao Jianda Xu Jinjun Hu Lili Han Shensheng
Executive Editorial Board
Wang Yongtian Liu Shu
Acta Optica Sinica,2020,Vol 40,No. 04
Cerebral ischemia is one of the common diseases in neurosurgery, and a rapid and accurate method for cerebral ischemia detection is urgently needed. Transmissive terahertz time-domain spectroscopy is applied to detect cerebral ischemic tissue. In order to reduce the impact of individual differences, the degree of ischemia of brain tissue is studied by calculating the relative difference of the terahertz absorption coefficients between the left and right brains. It is found that with the increase of ischemia time, the relative difference of absorption coefficient between the left and right brains of fresh tissue first increases and then decreases, which is mainly caused by the increase of water content and the decrease of cell density in the ischemic area; meanwhile, the relative difference of absorption coefficient between the left and right brains of paraffin-embedded cerebral ischemic tissue gradually decreases, which is mainly due to the gradual decrease of cell density in the ischemic region. The results show that the terahertz time-domain spectroscopy system can be used to detect the earliest 2 h cerebral ischemia, which provides an effective technical means for the early label-free rapid diagnosis of cerebral ischemia.