Sponsored by Chinese Society for Microbiology
ISSN 1000-8721 CN 11-1865/R
6 issues per year
Current Issue: Issue 03, 2020
Chinese Journal of Virology, an academic periodical established in 1985, publishes Original Articles, Brief Reports, Reviews, and so on, covering the advances and achievements of fundamental and applied research concerning human, animal, plant, and insect viruses as well as bacteriophages and prions. The subscribers of Chinese Journal of Virology are mainly workers in research institutes, universities, and other institutions of virological and biological studies in China, as well as world-known databases and libraries. Chinese Journal of Virology is supervised by the China Association for Science and Technology, sponsored by the Chinese Society for Microbiology, run by the National Institute for Viral Disease Control and Prevention, China CDC, and published by its Editorial Office. The International Standard Serial Number is ISSN 1000-8721; the Domestic Journal Number is CN 11-1865/R; the Domestic Postal Distribution Code is 82-227 (domestically distributed by all local post offices in China); the Overseas Distribution Code is BM6448 (distributed by China International Book Trading Corporation). Chinese Journal of Virology has been published bimonthly since 2005 and is now distributed worldwide. Chinese Journal of Virology is included in the Outstanding S&T Journals of China, Chinese Core Journals of Science and Technology, A Guide to the Core Journals of China (published by Peking University), Research Center for Chinese Science Evaluation, Wuhan University, and Chinese Science Citation Database source journals. In addition, it is indexed in CA, BA, CBST, MEDLINE (PubMed), and WPRIM. Chinese Journal of Virology has been included in the databases of CNKI (Disc Edition) since December 30, 2008. It began to tentatively offer Advance Online Publication in 2009 and has been formally offering Advance Online Publication since 2011. The composite impact factor of Chinese Journal of Virology is 1.355, according to the Annual Report for Chinese Academic Journal Impact Factors (Basic Medical Sciences) (2015, Volume 13), ranking top among the journals of basic medical and biological sciences. The homepage of Chinese Journal of Virology on CNKI is http://bdxb.cbpt.cnki.net. Chinese Journal of Virology started a pilot program of bilingual publication on November 8, 2016 to publish papers in both Chinese and English on CNKI net.
Honorary Editor-in-Chief: HOU Yunde
Editor-in-Chief: SHU Yuelong
LIU Xiufan, FANG Rongxiang, WU Guizhen, JIN Qi, LIANG Mifang, LI Mengfeng, XIA Ningshao, TAN Wenjie, XU Wenbo, WANG Yumei
Chinese Journal of Virology,2020,Vol 36,No. 03
Coronavirus disease 2019 (COVID-19) occurred as a new pneumonia of unknown cause at the end of 2019 and outbroke in the next two months in Wuhan. The scientific and effective understanding of the epidemic development is essential for its prevention and control. In this paper, a segmented Logistic model was built to describe confirmed cases, deaths and cured cases of COVID-19 based on the official data from National and Local Health Commissions. It is estimated that the total number of confirmed cases nationwide will reach 81,370 to 102,800, and the total number of deaths will reach 3,177 to 3,960, with a final mortality rate of 3.9%. All confirmed cases nationwide (deaths excluded) are expected to be cured on May 7, 2020 under current medical conditions and diagnostic criteria. The model can fit and forecast the trend of COVID-19 epidemic at two stages and provide a scientific basis for the epidemic prevention and control.
Chinese Journal of Virology,2020,Vol 36,No. 03
In order to understand the dynamic changes of virus-specific antibodies in the serum collected from coronavirus disease 19 (COVID-19) patients, three SARS-CoV-2 antibody detection kits with different principles were used in this study. Fifty-eight serum samples from 33 COVID-19 confirmed cases in Gansu Province, China were tested for virus-specific antibodies including IgM, IgG, and total antibodies. The detection results showed that the positive rates of IgM, IgG and total antibodies gradually increased with the time of onset: within the early 3 days, the positive rate of virus-specific antibody detected by three different kits ranged 13.6%–31.8%; within 4–7 days, the positive rate ranged 36.4%–45.5%; within 8–14 days, the positive rate ranged 55.6%–77.8%; after 15 days, the positive rate increased to 100%. In addition, three kits were used to detect serum samples collected from healthy people, and the specificity was 99%–100%. The statistical analysis indicated that there was no significant difference among the results of three kits ( P > 0.05). In summary, three different principles of SARS-CoV-2 antibody detection kits have good sensitivity and specificity, which can provide assistant for clinical diagnosis; in addition, the dynamic characteristics of virus specific antibody from serum obtained through this study provide an important scientific basis for studies such as epidemiological investigation and recessive infection study.