Chemical Constituents from Lagotis brachystachy

ZHU Ji-xiao1 SHI Ya-fu1 CHENG Hong-yu2 WANG Hong-ling1 WANG Rui1 LI Min1

(1.Research Center of Chinese Herbal Medicine and Ethnic Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, China 330004)
(2.School of Humanities, Jiangxi University of Traditional Chinese Medicine, Nanchang, China 330004)

【Abstract】Objective: To study the chemical constituents of Lagotis brachystachy. Methods: L. brachystachy was extracted with 75% ethanol and isolated and purified by silica gel, Sephadex LH-20, preparative liquid chromatography, ODS column chromatography, and recrystallization. The chemical structures were identified by spectrum analysis. Results: Eleven compounds were isolated and identified as scutellariosid II (1), globularimin (2), baldaccioside (3), 10-O-trans-isoferoylcatalpol (4), 8-epi-loganic acid (5), luteolin-7-O-β-D-glucopyranoside (6), tricin-7-O-β-D-glucopyranoside (7), luteolin (8), hemiphroside B (9), plantaginin D (10), benzyl alcohol-O-(2′-O-β-D-pyranoxylol)-β-D-glucopyranoside (11). Conclusion: Compounds 3, 4, 9, 10, and 11 are isolated from the Logotis genus for the first time. Compounds 1, 2, 5, and 7 are isolated from L. brachystachy for the first time.

【Keywords】 Lagotis brachystachy Maxim.; Chemical constituents; Structural identification;

【DOI】

【Funds】 National Natural Science Foundation of China (81660702) Open Fund of Jiangxi Collaborative Innovation Center of Modern Technology and Industrial Development of Ethnic Medicine (JXXT2017004)

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This Article

ISSN:1001-4454

CN: 44-1286/R

Vol 42, No. 03, Pages 552-555

March 2019

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Article Outline

Abstract

  • 1 Instruments and materials
  • 2 Extraction and isolation
  • 3 Structure identification
  • References