Chemical constituents of Eclipta prostrata
(2.Pharmacy Department, Peking University First Hospital, Beijing, China 100034)
(3.Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, China 100068)
(4.Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China 300193)
【Abstract】A total of twenty-two compounds were isolated from the 95% EtOH extract of Eclipta prostrata by various purification steps, and their structures were established as ecliptalignin A (1), ecliptasaponin Ⅰ (2), ecliptasaponin Ⅱ (3), echinocystic acid (4), 3-oxo-16α-hydroxy-olean-12-en-28-oic acid (5), acacetin-7-O-rutinoside (6), luteoloside (7), apigenin (8), luteolin (9), acacetin (10), skullcapflavone Ⅱ (11), kaempferol (12), kaempferide (13), quercetin (14), 4′, 7-dihydroxyl-3′, 6 ′-dimethoxylisoflavone-7-O-glucoside (15), ecliptal (16), 5-hydroxymethyl-(2, 2′, 5′, 2′′)-terthienyl tiglate (17), psoralen (18), isopsoralen (19), wedelolactone (20), crinumaquine (21), and 2, 3, 9, 12-tetramethoxyprotoberberine (22) mainly based on the spectroscopic techniques, of which 1 was a new lignin analogue, and 5, 6, 10–13, 15, 18, 19, 21 and 22 were isolated form this plant for the first time.
【Keywords】 Eclipta prostrata; Asteraceae; lignin; pentacyclic triterpene; flavone; thiophene; coumarin; alkaloid;
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Vol 43, No. 17, Pages 3498-3505