Sponsor(s): Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences; China Association of Acupuncture-Moxibustion
6 issues per year
Current Issue: Issue 05, 2020
Journal official website:http://xcyj.cbpt.cnki.net/WKA3/WebPublication/index.aspx?mid=xcyj
Acupuncture Research, the only journal in China that focus on the mechanism of acupuncture and moxibustion, is supervised by State Administration of Traditional Chinese Medicine of the People's Republic of China and sponsored by Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences and China Association of Acupuncture-Moxibustion. Launched in 1976, the journal is a sole academic journal mainly reporting the original experimental studies about the mechanism of the effects of acupuncture and moxibustion for treating common diseases. About 75% of these studies are subsidized by Chinese National Natural Science Foundation, Ministry of Science and Technology, Ministry of Education, State Administration of TCM, provincial (municipal) natural science foundation. The articles published in this journal no doubt reflect the highest level of scientific research in the field of acupuncturology in China. It is titled as the “Outstanding Scientific and Technological Journal of China” and “RCCSE Authoritative Academic Journal of China.” The journal is included in CA, CSCD.
Members of Editorial Board
Christopher John Zaslawski (Australia) CUI Jin(China)
DENG Liangyue(China) DING Guanghong(China)
DONG Guirong(China) FAN Yushan(China)
Effect of electroacupuncture on intestinal epithelial mucosal barrier function in rats with diarrhea-predominant irritable bowel syndrome
Acupuncture Research,2020,Vol 45,No. 05
Objective To observe the effect of electroacupuncture (EA) on intestinal epithelial mucosal barrier function in diarrhea-predominant irritable bowel syndrome (IBS-D) rats, so as to explore its mechanisms underlying improvement of IBS-D. Methods Forty SD rats (half males and half females in number) were randomly divided into control, model, EA and medication (pinaverium bromide) groups, with 10 rats in each group. The IBS-D model was established by chronic unpredictable mild stress combined with gavage of Folium Sennae solution. EA (2 Hz/15 Hz, 0.1–1 mA) was applied to unilateral Zusanli (ST36), Tianshu (ST25), Sanyinjiao (SP6) and Taichong (LR3) alternatively for 15 min, once daily for 14 days. Rats of the medication group was treated by gavage of PB (10 mL·kg −1·d −1) for 14 days. The visceral sensitivity (pain) was assessed by using the pressure threshold which the inserted rectal balloon catheter air-inflation (connected to a blood pressure gauge) induced stronger abdominal muscular contraction to force the rat’s abdomen to lift the experimental stand surface. The diarrhea index was used to evaluate loose stool grade. The expression of Claudin-1 and Occludin (intestinal epithelial tight junction proteins) of colon tissue was detected by immunohistochemistry. The activity of plasma diamine oxidase (DAO) was assayed by using spectrophotometry. Results Compared with the control group, the diarrhea index and plasma DAO activity in the model group were significantly increased ( P < 0.01), while the visceral pain threshold, expression of Claudin-1 and Occludin in the model group were significantly decreased ( P < 0.01). After the treatment, the diarrhea index and plasma DAO activity were significantly lower in both EA and medication groups than that in the model group ( P < 0.01), and the visceral pain threshold and expression levels of Claudin-1 and Occludin were obviously increased ( P < 0.05, P < 0.01). No significant differences were found between the EA and medication groups in all the above-mentioned indexes ( P > 0.05). Conclusion Electroacupuncture can significantly improve abdominal pain and diarrhea in IBS-D model rats, which may be closely associated with its effects in up-regulating the expression of intestinal epithelial tight junction proteins Claudin-1 and Occludin to restore the function of intestinal epithelial mucosal barrier.
Encircling needling is superior to “Bangci” (adjacent needling) in promoting wound healing in diabetic mice
Acupuncture Research,2020,Vol 45,No. 05
Objective To compare the therapeutic effects of “Bangci” (adjacent needling) and encircling needling in promoting skin wound healing and local blood perfusion in diabetic mice. Methods Thirty-two male C57 BL/6 N mice were randomized into a normal group, a model group, an adjacent needling group, and an encircling needling group, with eight mice in each group. The skin wound model was prepared by cutting a piece of full-thickness skin on the back of mouse with a puncher. One hour after modeling, two acupuncture needles were respectively inserted into the center of the wound and the spot at the normal skin about 0.5 cm away from the edge of the wound for mice of the adjacent needling group, followed by EA (0.5 mA and 0.5 Hz) stimulation for 30 min. For mice of the encircling needling group, four acupuncture needles were respectively inserted into the upper, lower, left and right sites 0.5 cm away from the wound edges, followed by EA stimulation at the same parameters as those for the adjacent needling group. The wound conditions, diameter and area of the wound were monitored, and the wound blood perfusion volume was measured by using a laser speckle flowmeter. Results The wound shrinkage rates in both adjacent needling and encircling needling groups on the 3rd, 5th, 7th, 9th and 11th days after modeling were significantly higher than those in the model group ( P < 0.05). The wound shrinkage rates in the encircling needling group on days 3, 5, 7 and 9 were also significantly higher than those in the adjacent needling group ( P < 0.05). The wound healing time in both adjacent needling and encircling needling groups was obviously shorter than that in the model group ( P < 0.05), and the wound healing time in the encircling needling group was also shorter than that in the adjacent needling group ( P < 0.05). Following modeling, the wound blood perfusion volume was in the model group was considerably higher from days 1 to 9 and markedly lower on day 11 than that in the normal group ( P < 0.01). After the intervention, the blood perfusion volumes were considerably decreased on days 3, 5, 7 and 9 in both the adjacent needling and encircling needling groups ( P < 0.05, P < 0.01), and obviously increased on day 11 in the encircling needling group relevant to those in the model group ( P < 0.01). Comparison between post-and pre-EA stimulation showed that the blood perfusion volumes immediately after intervention were significantly increased from days 1 to 11 in both the adjacent needling and encircling needling groups ( P < 0.01, P < 0.05). The encircling needling was significantly superior to the adjacent needling in lowering the blood perfusion volume from days 3 to 7, and in increasing the blood perfusion volume on days 9 and 11 ( P < 0.01). With the naked eyes, the conditions of exudation and inflammatory reaction, and the scar and granulation tissue in both the adjacent needling and encircling needling groups were relatively milder than those in the model group. Conclusion Both adjacent needling and encircling needling can promote the skin wound healing by increasing the blood perfusion volume in diabetic mice, and the therapeutic effect of the encircling needling is significantly superior to that of the adjacent needling.
Feasibility Analysis on Acupuncture Therapy for the Treatment of COVID-19 and Exploration on Application Scheme
Acupuncture Research,2020,Vol 45,No. 05
The situation of Coronavirus Disease 2019 (COVID-19) is still severe at present. In order to better fight against the epidemic and give full play to the advantages of traditional Chinese medicine, we explored the feasibility of acupuncture therapy in the intervention of COVID-19 through analyzing the relevant literature in both ancient and modern times. Additionally, we analyzed the acupuncture intervention scheme for COVID-19 developed by China Association of Acupuncture and Moxibustion and supplemented the intervention protocol with auricular acupuncture. It was proposed that the advantages of acupuncture and moxibustion should be fully displayed when Chinese medicine is applied in the treatment of COVID-19. During the treatment, acupuncturists should be rationally allocated to adequately utilize comprehensive therapeutic approaches and guarantee people’s safety to the greatest extent. Eventually, we can improve the clinical therapeutic effect, save national resources and conquer the COVID-19 epidemic early.